Down in the Dumps

Do you ever get to the point where it seems like no matter how hard you try, nothing seems to go right? It seems like things just keep spinning out of control until they are so far gone, it seems like there are no ways to fix it? It feels like a downward spiral. I want to go up, not down, and now matter how hard I cling and try to climb, I keep going down. I don't know what is left to do. I have been on my knees, in tears, literally crying out to God. I feel as if my prayers are falling on deaf ears. I hope that God is hearing me and will soon give me an answer.